Pharmaceutical Development

Bettersize instruments provide test data of particle size distribution and the physical performance of powder so as to contribute to the whole process of pharmaceutical research, development and production. Grain size measurement attaches great importance to the pharmaceutical industry.

Among pharmaceutical products, solid pharmaceutical preparations account for about 70% – 80%. They include powders, granulates, capsules, tablets, powder filling, suspensions, etc. The unit operations involved consist of smashing, grading, mixing, pelleting, drying, preforming, packaging, transportation and storage. In the preparation process, most solid preparations need to be further processed to improve their powder properties so as to meet the requirements of pharmaceutical quality and operation. The grain size analysis of pharmaceutical particles can also affect the release of the drug, thereby affecting its efficacy and toxicity. For example, if the pharmaceutical particles are too large, the drug will not be properly released, and if the pharmaceutical particles are too small, the drug will be released too quickly, which will increase toxicity and the possibility of side effects. Bettersize grain size analysis software can help you solve these problems. Our particle size analyzers, such as Bettersizer S3 Plus, Bettersizer 2600, etc, have been widely used in the pharmaceutical industry for grain size determination.

Bettersize instruments accurately measure particle size distribution, particle shape, powder flowability, tap density, bulk density and porosity. This assists in the whole process of pharmaceutical research, development and production.

We provide customers with convenient measuring instruments and accurate analysis results. The analysis results conform to 21CFR Part 11.

Mining and Minerals

Bettersize particle shape analyzer are widely used in the research, manufacturing and application of all kinds of mining and minerals, bringing favorable profits.

The Bettersize particle shape analysis machine and powder characteristics tester can provide complete physical property analysis and granulometry analysis for the deep processing of mining and minerals, and offer data including particle size distribution, particle shape, flowability, tap density and bulk density, helping you to reduce the cost of mineral processing and control the correct particle grades of products.

Abrasives, Fluorspar, Gallium, Mica, Soda Ash, Antimony, Garnet, Molybdenum, Arsenic, Nickel, Strontium, Asbestos, Germanium, Niobium, Sulfur, Barite, Gold, Talc, Bauxite, Graphite, Tantalum, Beryllium, Gypsum, Perlite, Tellurium, Bismuth, Hafnium, Phosphate Rock, Thallium, Boron, Platinum, Thorium, Bromine, Indium, Potash, Tin, Cadmium, Iodine, Pumice, Titanium, Cement, Iron and Steel, Quartz Crystal, Tungsten, Cesium, Iron Ore, Rare Earths, Vanadium, Chromium, Iron Oxide Pigments, Rhenium, Vermiculite, Clays, Kyanite, Rubidium, Wollastonite, Cobalt, Lead, Yttrium, Copper, Lime, Sand, Zeolites, Diamond, Lithium, Scandium, Zinc, Diatomite, Magnesium, Selenium, Zirconium, Feldspar, Manganese and Silicon are all materials that are mined and then extracted from the ore. If it is mined, particle size distribution measurement in the extraction of useful minerals is an arduous and technically demanding. The ore is blasted or cut and loaded and hauled to the mill for the secondary crushing and grinding which prepares the material for its intended use.

Comminution

In many cases, the valuable minerals are mixed with gangue and the ore must be separated. The first step of many separation processes is comminution (size reduction) followed by classification (separation by particle size) either for further grinding or the next step, concentration of the ore. During comminution, ore must be ground such that the particles are small enough that each particle consists of primarily one mineral. These particles are then separated to concentrate the mineral product.

Gravity Separation

Gravity separation relies on differences in material mass to separate minerals. Methods include jigs, sluices, spirals, shaking tables, fine particle separators, and hydrosizers and cyclones. Gravity separation is separation based on weight only and is directly affected by particle size since volume is proportional to weight.

Jigging uses pulsed water flow or a similar process to push up ground material. Heavier and larger particles will sink more quickly between pulses and thus tend to the bottom of the jig. Thus, uniform particle size is important to ensure separation by density and not size. In addition, jig operation (length of water pulses) and design will depend on the size of particles being separated. Sluices and spirals rely on the difference between viscous drag and buoyancy for particle separation. This difference is directly related to particle size. Gravity tables use a vibrating platform to separate by particle size and specific gravity. Thus, narrow size distribution feeds result in better separation.

Froth Flotation.

Here the material is separated by surface chemistry. Bubbles flowing through a slurry or suspension will tend to stick to particles with a hydrophobic surface and cause the particles to float to the top of a froth for recovery. Often, particle surfaces are selectively modified so that mineral surfaces are hydrophobic while gangue surfaces are hydrophilic. Particle size is important to the process efficiency. Overly fine particles may be entrained in the bubble flow regardless of surface chemistry, reducing the effectiveness of separation efficiency. Overly large particles will tend to sink regardless of bubble attachment.

Electrostatic and Magnetic Separation

The behavior of a particle under electrostatic or magnetic fields can be exploited to separate particles by type. These fields will induce charges (or magnetism). The resulting forces will cause particles to move depending on particle mass. Thus small particles are moved further than large particles. Furthermore, particle charge is a surface phenomena and the larger surface area of fine particles will tend to have a higher charge. These size effects can lead to separation by size rather than composition. As such, a narrow size distribution often, but not always leads to better separation.

Shipping Product

The final product is often graded and sold as-is or for further processing. Users will want a particular particle size range in order to ensure that their process is optimized. Thus, in the all-important step of selling products, many mines will control particle size and in some cases, particle shape is important as well.

The particle sizing systems below are fully capable of measuring size and shape to assist the user to obtain the optimal size throughout the manufacturing process.

Food and Beverage

The particle size distribution testing of the food and beverage industry provides necessary data for improving quality and production efficiency.Therefore, particle size analyzer plays an important role in particle size analysis of food and beverage industry. Bettersize laser particle size analyzer has been widely used in the food and beverage industry for its stable performance, high repeatability and accuracy in particle size measurement.

The performance of the food and beverage industry is closely related to the quality and safety of its products. Further challenges include organoleptic quality, guarantee period, stability, process stability and quality control. The morphology of food is various, including solid state, liquid state, powder, powders and viscous emulsions, and some food at the intermediate production stage is in a powder form. The particle size analyzer can provide scientific data to ensure that production in the intermediate and final stages can meet the standards, thereby providing scientific and effective quality control.The performance of the food and beverage industry is closely related to the quality and safety of its products. Further challenges include organoleptic quality, guarantee period, stability, process stability and quality control. The morphology of food is various, including solid state, liquid state, powder, powders and viscous emulsions, and some food at the intermediate production stage is in a powder form. The particle size analyzer can provide scientific data to ensure that production in the intermediate and final stages can meet the standards, thereby providing scientific and effective quality control. Bettersize particle measuring systems meet the international standard with high accuracy, which has attracted great attention of customers in the food and beverage industry and has been widely used in the particle size analysis lab such as coffee and other products.

One example where tight particle size control is required is in the manufacture of chocolate. In the first stage, the nibs are ground into a thick paste called the chocolate liquor. The size of the particles in the chocolate mass is now about 100 microns. To avoid a grainy taste in the finished chocolate, another grinding takes place to reduce the particle size to about 18 microns as the tongue can sense grains of 18 microns or larger. If cocoa powder is being made, the chocolate liquor is further processed into pressed cake, and cocoa butter produced. .The chocolate liquor or mass is put into hydraulic presses under extremely high pressure to drain off the clear, golden liquid cocoa butter. The press cake that is left is cooled, pulverized and sifted into cocoa powder. At this stage the chocolate liquor and other ingredients are kneaded together according to the kind and quality of the chocolate being made. The cocoa liquor is mixed with cocoa butter and sugar and this is further refined by reducing the particle size of the added milk powder solids and sugar down to the desired fineness. The Cocoa powder or ‘mass’ is blended back with the cocoa butter (added to promote better mouth feel and reduce the viscosity) and liquor in varying quantities to make different types of chocolate. Lecithin, an emulsifier, which is much cheaper than cocoa butter $2577/ton (£1,577/ton) is also used to reduce the viscosity of chocolate and so reduces the amount of extra cocoa butter that must be added.

The ingredients can be churned together for hours. The resulting mixture is then dried to form a crumb which is ground with more cocoa butter in the next phase to make the thick chocolate crumb into a silky chocolate. This step reduces the particle size of the cocoa mass to 25 to 30 microns. The smoother the chocolate desired, the more time spent in the rolling mill.

No matter which solid, liquid or emulsion you use, the Bettersize particle size and particle shape analysis system can help you to:

● Rapidly test the particle size and particle shape of new formulations, and participate in new product development

● Optimize the powdering and pelleting process

● Control production and ensure the consistency of ingredients

● Participate in quality control and improve productivity and throughput

BT-Online1

Online Particle Size Analyzer

BT-Online1 Online Particle Size Analyzer is an online particle size analysis monitoring system for real-time particle size monitoring and control in powder manufacturing industries. Driven by Standard Operation Procedure (SOP), the particle size monitor automatically samples, measures, recovers and processes data directly from the powder delivery pipeline, providing 24-hour particle size detection and control for a variety of dry powder production lines.

Measurement: Particle size

Particle size range: 0.1 to 1000µm

Dispersion type: Dry

Technology: Laser diffraction

Features and Benefits

Measuring range: 0.1 – 1000 µm

Repeatability: ≤3% (GBRM D50)

Accuracy: ≤3% (GBRM D50)

SOP: Standard Operation Procedure

Detectors: 68 pieces

Test speed: ≤1 min

High-performance semiconductor laser with long lifespan

Automatic Alignment

Automatic Centering

1. Real-time Control System

As well as being able to continuously monitor particle size, the system also has a function for real-time feedback and control. The system will collect real-time size data and perform calculations against the particle size control limits. It automatically generates the feedback signal to the control center. This closed loop feedback control system will achieve better quality improvement, higher efficiency, reduce wastage and save energy.

Real-time Control System

2. Automatic Centering Guarantees perfect conditions of the optical system

By moving the laser detector center point to the focus point of the lens before each test, the automatic centering function guarantees perfect conditions of the optical system, therefore providing accurate and repeatable testing results.

Automatic centering3. Accuracy Calibration Maintain accurate datum lifetime

This function maintains operating parameters at consistent conditions, producing consistent and reproducible measurement across the board for all instruments, old and new.

Accuracy calibration

4. Reliable Sampling System

Sample dispersion is achieved by accelerating the powder through a venturi. The “backflush” and tapered pipe design prevents blockage of the sampling tube, and keeps the residual powder clean, ensuring the accuracy and continuity of real-time testing.

Three different dispersion mechanisms can act upon the sample:

Three different dispersion mechanisms

5. Versatile Functionality of the System

The system has power interruption protection and over-pressured protection functions. Under these abnormal operating conditions, it will initiate an automatic shutdown

sequence to protect the system from harm. The electrical and mechanical system of the BT-online1 has robust interference protections; it is ready for the haphazard nature of a production environment and an electromagnetic interference prone environment.

6. Contamination Prevention Optics System

Using the controlled principle of aerodynamics, we devised the double air-cushion lens protection system. The contamination prevention technology will form an invisible double air shield between the sample stream and the lens, eliminating the optics from contamination from sampling, as well as a dust-prone environment. With this technology, the ultimate goal of a long duration of sustainable operation, providing real-time, continuous particle size monitoring and control can be realized. Accuracy and continuous monitoring of the production data can be achieved.

Specification

BT-Online 1
Particle size distributionDry powder
TheoryLaser diffraction
Analysis theoryMie and Fraunhofer
Typical interval measurement time≥1 min
Measurement range0.1 – 1000µm
Number of size classes88 customized grades
Accuracy≤3% (GBRM D50)
Repeatability≤3% (GBRM D50)
Resolution ratioSingle peak, double peak, multi-peak
Red lightMax. 3mW, Semiconductor optical fiber laser, 635nm
Lens arrangementSingle lens
Lens designF-Theta Lenses
Effective focal length223mm
ArrangementLog-spaced array
Quantity68 pieces
Light path adjustmentIntelligent automatic alignment
Dispersion typeDry 
Air flowrate400-6000L/min
Pressure0.5-0.8MPa
Air filter0.3µm, 0.01µm, water, oil
21 CFR Part 11Enable
SOP DesignerEnable
ReportMore than 14 formats report
Auto testEnable
Data exportEXCEL, PDF, WORD, JPG and etc.
Laser classClass I laser product
Supply voltage220VAC
Dimension800mm x 280mm x 280mm (L x W x H)
Weight21kg
Computer interfaceAt least one USB2.0 port required
Operation systemWindows XP, Windows 7,8 or 10
Hardware specificationIntel Core I5, 4GB RAM, 250GB HD

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At Bettersize, our mission is to provide best-in-class particle size measurement units, comprehensive solutions and exceptional customer services. We are dedicated to assist scientists, researchers and engineers around the world to understand material properties, facilitate research, improve production efficiency and beyond.

Founded in 1995, Bettersize is China’s No. 1 player in laser particle sizing business, in the most recent years, Bettersize has gained increasing significance at the global market, offering a wide variety of products from basic to advanced research equipment, delivering precise analysis of materials from nanometer to millimeter.

BeVision D2

Dynamic Image Analysis Particle Size

The BeVision D2 provides an efficient solution to the size and shape analysis of dry, high-flowability powders or granules. Tens of thousands of particles can be measured by a BeVision D2 within three minutes. Combining a high-speed camera with a precise telecentric lens, the BeVision D2 is able to efficiently analyze the size and shape of particles in the range of 30 – 10,000 µm. The BeVision software helps you evaluate particle size and shape from 24 different aspects and further organizes the data into an all-around validation of particles.

Measurement range: 30 – 10,000 µm

24 different laser particle sizing and shape parameters

Reduction of workload and time

Outstanding reproducibility

Results in compliance with ISO 9276-6

Fully automated operation

Powerful particle size image analysis software provides a comprehensive evaluation

Comparable with sieving results

•Why Image Analysis Method?

Easy

Capture an image of particles, identify particles, then measure their size and shape. Every step of image analysis is easy and clear.

Shape analysis

Based on a direct view of particles, it is possible to analyze not only the size of particles, but also their shape.

Seeing is believing

The image analysis method determines the size and shape of every individual particle and then sums it up to form a statistic. Details of particle size or shape distribution can be accurately provided.

•Why Dynamic Image Analysis Method?

Efficiency

A continuous particle flow passing through the measurement zone helps achieve a higher efficiency of the measurement.

Oversized particle sensitivity

The dynamic image analysis method is sensitive to oversized particles; it is even possible to estimate the size of oversized particles.

Reliable results

The maximized number of measured particles ensures the statistical significance of measurement results.

•BeVision D2 Hardware: Guaranteed Accuracy and Efficiency for You

To measure the size and shape of particles over a great variety of applications, the BeVision D2 has equipped with a comprehensive range of hardware. Corresponding to the sample material properties, selecting the best hardware can help measure the size and shape of particles with optimum accuracy and efficiency.

•Particle Size and Shape Parameters:

Size parameters

Equivalent diameters: area-equivalent diameter、perimeter-equivalent diameter; Feret diameters: maximum and minimum Feret diameters,  XLF (“length”)

Martin diameters: maximum and minimum Martin diameters; Legendre ellipse: major and minor axes

Shape parameters

Size difference in 2 directions: aspect ratio、L/W ratio、ellipse ratio; Round-likeness and rectangle-likeness: Circularity、irregularity、compactness、extent、box ratio

Contour concavity: Concavity、convexity、solidity; For elongated particles: Elongation、straightness

•BeVision Software: Visualized Insights for You:

•Typical Applications:

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Bettersizer ST

The Bettersizer ST is an automated laser scattering particle size distribution analyzer designed for industrial quality control. Its patented DLOS (Dual Lens Optical System) guarantees the instrument to provide consistent and reliable particle size distribution results. The SOP (Standard Operating Procedure) and automated analysis procedures are designed to help you save valuable time for quality inspection. Skip complex operations with Bettersizer ST: Simply click “Start”, add the sample, and Bettersizer ST will provide the particle size distribution analysis for you.

Measurement: Particle size

Particle size range: 0.1 to 1000µm

Dispersion type: Wet

Technology: Laser diffraction

Analysis: Mie scattering theory and Fraunhofer diffraction theory

Detector: 86 high-speed photodetectors (forward, lateral and backward arrangements)

Measuring angle: 0.031-159°

EXCELLENT ACCURACY

Accuracy Verification of Standards

Duke standard samples were measured separately by the Bettersizer ST laser particle sizer, showing the distribution peak in the correct position and narrow distribution with high accuracy.

The red line is the nominal size range of standards ± 1.0%, and the black dots are the measured sizes. As shown in the figure, the measurement accuracy of Bettersizer ST laser particle sizer for standards is within 1%.

OUTSTANDING REPEATABILITY

Exceptional repeatability provided by Bettersizer ST laser particle size instrument ensures the reliability of the results. Rapid measurements with consistent and reliable results can ease your workload on quality control.

Excellent Repeatability From: – Stability of signal transmission systems – Efficient dispersion system – Automatic alignment keeps the instrument always in optimum condition – Signal acquiring rate up to 3500 times/second

Repeatability Tests

The outstanding repeatability of Bettersizer ST, demonstrated by the following two consecutive tests.

Legendary Ease-of-Use

The Bettersize software provides various functions that greatly reduce your workload.

Ⅰ . Intuitive Software

Ⅱ . Intelligent Data Evaluation for Quality Control

Ⅲ . Performance Validation

Ⅳ . System Inspection

Cost-Efficiency & Robustness

Outstanding Robustness

– Integrated casting of the bottom plate to protect the instrument

– Accurate measurements can be achieved even after a robustness test

– Long-life fiber semiconductor laser source

– Durable circulation tank with casted stainless steel

– Power-adjustable ultrasonic disperser with dry run protection

Compact Design

– Save valuable workspace for factories and laboratories with an internal wet dispersion system

– The DLOS ensures result accuracy and reliability, while avoiding folding optics that are susceptible to misalignment

Simple Maintenance

– Simple disassembly of sample cells allows a quick cleaning, which can be easily accessed without professional tools and excessive clean formulations

– Auto-cleaning function for the circulation tank eases the maintenance work greatly

– Auto-cleaning process can be easily customized in the software

Low Cost of Ownership

– Entry-level price for a laser particle size analyzer 

– A measurement range that covers most applications can be achieved with DLOS without additional cost for a second laser source

Specification

Parameters Measured
Particle size distributionSuspensions, emulsions, dry powders
General
PrincipleLaser diffraction technology
AnalysisMie scattering theory and Fraunhofer diffraction theory
Typical measurement timeLess than 10 seconds
Measurement Performance
Measurement range0.1 µm – 1000 µm
Accuracy error≤1% (NIST certified standards)
Repeatability error≤1% (NIST certified standards)
Number of size classes≤100 (adjustable)
Feeding modeAutomatic wet circulation
Main Device
Optical systemPatented DLOS (Dual Lens Optical Systems)
LaserHigh-power fiber semiconductor laser (10 mW/635 nm)
Detector86 photodetectors (forward, lateral and backward arrangements)
Measuring angle0.031 – 159°
Dispersion Module
Circulation speed300 – 2500 r/min
Circulation flow rate3,000 – 8,000 mL/min
UltrasonicationDry run protection, Max 50 W (adjustable)
Circulation tank capacity600 mL
Software
Conformity21 CFR Part 11, ISO 13320, CE
ReportsCustomizable reporting
System Parameters
Dimensions (L x W x H)660 x 420 x 320 mm
Weight38 KG
VoltageDC 24V, 221 W
Computer Configuration (Recommended)
Computer interfaceAt least one high-speed USB 2.0 or USB 3.0 port required
Operating systemWindows 7 or higher
Hardware specificationIntel Core I5, 4GB RAM, 250GB HD

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Bettersizer 2600

Laser Particle Size Analyzer (Dry & Wet Dispersions)

The Bettersizer 2600 utilizes this laser diffraction technology. There are 92 photoelectric detectors to convert light signals from the scattering spectrum to electrical signals, which are transmitted into an intelligent software. By implementing the Mie scattering theory to the data and performing mathematical conversion, the complete particle size distribution can be derived.

Measurement: Particle size

Particle size range:

Wet dispersion: 0.02 to 2600μm

Dry dispersion: 0.1 to 2600μm

Dispersion type: Wet and Dry

Technology: Laser diffraction

Precise measurement of both large and small particles covering the broadest range by a new patented technology utilizing both Fourier and Reverse Fourier optical systems

Optical bench with 92 detectors covering an angular range of 0.016° – 165°

Optional wet and/or dry dispersion

Small volume dry dispersing module for small sample quantities especially for pharmaceutical or valuable samples in short supply

Easy and fast to changeover between dispersing modules

Easy to implement, create and use Standard Operation Procedures for new materials

Automatic alignment of the optical system

User-friendly software, easily learnt

1)FOURIER AND REVERSE FOURIER OPTICAL SYSTEM

The Bettersizer 2600 is superior in the combination of Fourier and inverse Fourier design. This smart design allows, on the one hand, the detection of stray light in a very wide angular range from 0.016° to 165°. On the other hand, in contrast to the inverse Fourier design, the particles do not have to lie on one plane – the simultaneously accurate measurement of small and large particles is therefore achieved.

Features of combination of Fourier and inverse Fourier design

Spherical detector array: Forward, lateral and backward detectors in 92 pieces in total;

Super large Fourier lens;

Small footprint: Compact design to save space

2)INTUITIVE AND POWERFUL SOFTWARE

Intuitive operation and orderly user interface

Real-time mode for determining the optimal measurement conditions

Fully automatic measurement routine

Automatic cleaning routine

Automatic data backup and highly customizable reports

Direct conversion according to Fraunhofer and Mie evaluation models

Switch between wet and dry dispersion modules with one click

3)WET DISPERSION

BT-802 is designed for particle size measurement with water as the medium.

BT-802 is made up of ABS shell. The components of it include centrifugal pump, peristaltic pump, ultrasonic disperser, pinch valve, control circuit, etc. The stirring speed is adjustable from 500 – 2500 rpm. Built-in ultrasonic system (50 W) ensures stable dispersion of samples.

BT-80N is designed for particle size measurements with organic solvents as the media. BT-80N is suitable for common organic solvents, for example:

Ethanol Methanol Isopropanol Ether

Toluene Xylene Dichloromethane Octane

Ethyl acetate Acetone Methyl oleate NMP solvents

BT-80N is made up of stainlesssteel shell. The components of it include centrifugal pump, ultrasonic disperser, PTFE pipeline, sintered-quartz sample cell, control circuit, etc.

Wet Small Volume Dispersion Module is designed for valuable or small-volume sample measurements, where the medium is solvent or water. The module consists of ABS shell, stirring motor, cuvette (8 ml), stirrer, etc.

Maximum volume in 8 mL with samples mass in 0.005 – 0.1 g.

Suitable for samples dispersed in water or organic phase.

4)DRY DISPERSION

BT-902 is suitable for dry powders particle size measurement units. The gas used can be compressed air, nitrogen or other noble gases.

BT-902 is made up of electromagnetic vibration feeder, venturi pipe, gas circuit, electric circuit, pressure sensor, etc.

BT-903 is designed for particle size instruments of valuable and small amount dry powders with a minimum samples volume of 20 mg.

BT-903 is composed of venturi pipe, gas circuit, electric circuit, samples tube, etc.

5)Application

Bettersizer 2600 
Parameters measuredMaterials
Particle size distributionSuspensions, emulsions, dry powders
General 
PrincipleLaser light scattering
AnalysisMie and Fraunhofer scattering
Typical measurement timeLess than 10 seconds
Measurement performance 
Measuring range0.02 – 2600 μm (wet) *0.1 – 2600 μm (dry) *
Accuracy error≤ 0.5% *
Repeatability≤ 0.5% *
Reproducibility≤ 0.5% *
Number of size classes100 (user adjustable)
Feeding modeAutomatic circulation or micro cuvette (wet)Gas transportation (dry)
Special functionsSOP settings, refractive index measurement, sample ratio calculation
Main device 
Optical systemCombined Fourier and inverse Fourier & Tilted sample cell
LaserHigh-power optical fiber laser (10 mW / 635 nm)
Detector92 detectors (forward, lateral and backward arrangements)
Measuring angle0.016 – 165°
Wet dispersion module 
Measurement methodOne-click operation (automated measurement, cleaning, saving, printing, etc.)
Dispersion mediumWater or organic solvents (sample dependent)
Circulation speed300 – 2500 r/min
Circulation flow3000 – 8000 ml/min
UltrasonicationDry burning prevention,1 – 50 W
Dry dispersion module 
Dispersion mediumAir/ Nitrogen/Noble gas
Air pressure0.1 – 0.8 MPa (Air compressor dependent)
Gas flow400 – 6000 L/min
Software 
Conformity21 CFR Part 11, ISO 13320, USP <429>, CE
ReportsCustomizable reporting
System parameters 
Dimensions (L x W x H)70.5 x 31.8 x 29.5 cm
Weight23 kg
Supply voltage100 – 240V, 50/60 Hz
Computer configuration (recommended) 
Computer interfaceAt least one high speed USB 2.0 or USB 3.0 port required
Operating systemWindows 7 (32 bit and 64 bit) or higher
Hardware specificationIntel Core i5 Processor, 4GB RAM, 250GB HD, Wide screen monitor

Now the particle size analyzer price is low, anything you need, please contact us.

BeDensi T Pro Series

The BeDensi T Pro Series with up to 3 workstations excels at intuitive operation while complying with the United States Pharmacopeia (USP <616>), European Pharmacopeia (EP2.9.34), ASTM and ISO. This tap density meter consists of the main body, control panel, graduated cylinders and embedded mini printer. It has adjustable tapping frequency and numbers. In addition, the drop height (3 or 14 mm) and cylinder types (25, 100 and 250 ml) are also available according to different requirements. The BeDensi T Pro Series is the ideal tester to determine the tapped density of different powders in various industries, such as pharmaceuticals, metallic powders and compounds, chemistry, batteries, food and beverage, carbon and ceramics.

1) Compliance (USP/EP/ISO/ASTM)

2) Easy to use

3) Up to three workstations

4) Wallet-friendly

Features

Compliance

Meeting the USP, EP, ASTM and ISO standards to provide informative results.

Easy to Use

Set standard test conditions easily with membrane keypad

Replace cylinders quickly with the easy lock holders

One click to print detailed parameter reports on completion of a test

Up to 3 workstations

The single tap density apparatus with up to 3 workstations to meet different measurement needs and scale up your productivity even further

Wallet-friendly

Own a reliable tapped density tester at an affordable tapped density tester price

Performance

The 10 cycle measurements of two samples demonstrate the excellent repeatability (<1.0%) of the BeDensi T Pro Series.

Standardized and elaborated design ensures the tapped bulk density measurement can provide reliable and informative results.

Application

Pharmaceutical

Metal Powder and Compounds

Batteries

Food and Beverage

Carbon

Ceramics

Chemistry

BeDensi T Pro Series
Test WorkstationUp to 3 
ComplianceUSP<616>, 
EP 2.9.34, 
ASTM D7481 
ASTM B527 
ISO 787-11 
User defined 
Taps1 to 99999 
Speed100 to 300 taps/min (adjustable) 
Drop Height3 ± 0.2 mmFor nominally 250 + 15 taps/min
14 ± 2 mmFor nominally 300 + 15 taps/min
Graduated Cylinder25 mlReadable to 0.2 ml
100 mlReadable to 1 ml
250 mlReadable to 2 ml
Repeatability≤1% 
Power100-240VAC/50-60 Hz/ 50 W 
DimensionsWidth260 mm
Depth410 mm
Height245 mm
WeightT116 kg
T218.2 kg
T321 kg

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As a particle size analyzer instrument manufacturer, we will do our best to meet all the needs of customers.

BeDensi B1

BeDensi B1 powder bulk density measurement equipment adopts natural deposition method. The manufacturing standard of this density measuring instrument meets the criterion of GB / T16913.3-1997- Part III: Determination of bulk density.

Measurement: Bulk density

Testing sample: except for metal powder

Technology: natural deposition

Manual Operation Bulk Density Test Apparatus

The BeDensi B1 powder bulk density tester is mainly used for the analysis of bulk density for different powders (except for metal powder), which adopts the natural deposition method. Fully in accordance with GB / T16913.3-1997- Part III:Determination of bulk density.

We can offer kinds of particle size measurement units for sale, if you have needs to buy a laser particle sizer, please leave us a message.

Image Analysis

Image Particle Analysis

Most particle size measurement techniques methods are based on the assumption of spherical shaped particles. This hypothesis leads to significant errors in the analysis if the particles are flake or rod-shaped. Especially for such highly form-anisotropic particles, automated imaging provides an excellent alternative for the determination of tailor-made size specifications.

Automated imaging methods for the determination of the particle size distribution of a material offers a fundamental advantage over alternative methods such as static light scattering, sedimentation or sieving: Each particle is photographed individually! This results in several important advantages for the determination of the particle size distribution:

Realistic proportional values also at the edges of the size distribution, i. e. detection of oversized particles or fine particles

Visual assessment of the dispersing state of a sample (dispersing quality, presence of agglomerates)

Calculation of meaningful size parameters, e. g. geodetic length or Feret diameter for fibres, depending on the application

Selection of the appropriate distribution type (volume, number) depending on the particular task

In addition, the individual photography of the particles gives the opportunity to make statistical calculations on the particle shape, which in practice enables further differentiation of materials. For example, form anisotropy, the deviation of the particles from the ideal sphere, often plays a decisive role for their application and further processing – for example, the conveyance or compaction of powders, the influence on the rheology in dispersions or, in addition to the particle size distribution, the roughness of the particle surface plays an important role for the success of shaping or polishing.

The necessity for tailor-made particle size and shape parameters, combined with ever-increasing PC processing power, ensures that automated imaging methods are becoming increasingly more relevant to a market which is 95% non-spherical..

Measurement method

The determination of the particle shape by automated imaging includes 4 basic steps:

1. Image taking

2. Image processing

3. Object detection

4. Classification

The image taking is ensured by special digital cameras, if necessary in combination to a microscope, to enlarge the particles. The particles may be present neutral (e.g. on an objective) or in motion as well. The dispersing (separation) of particles is possible both in dry-mode (e.g. by simple conveying and riddling or by the usage of compressed air) but also in wet-mode in a solvent. An absolutely basic requirement to perform a successful particle shape analysis is high resolution, image sharpness, good sample dispersing resulting in measurement of individual particles and suitable enlargement. More explanation of this expression required etc. Image processing by appropriate software leads to upgraded pictures: for example isolated pixels and edging particles are eliminated, variations in brightness and signal noise are retouched and agglomerated particles are separated. The main part in object detection is image binarization, whereby every image pixel is assigned to a particle (black) or the background (white) using a threshold. The recognition of objects (particles) and feature attribution is realized by the software. In the last step, the classification, the particles are arranged in classes (e.g. size equivalent classes) on the basis of their attributed features (size and shape parameters).

Numerous size and shape parameters can be determined from the particles images by the appropriate software. Important size parameters are for example (CE) equivalent disc diameter Deq, maximum inscribed disc diameter Din, fiber length XLG (geodesic length) and fiber diameter XFD.

The equivalent disc diameter corresponds to the disc diameter of identical area to 2-D-projected particles, which is often used as size indicator for irregular shaped particles in process technology. On the contrary the maximum inscribed disc diameter of the 2-D-projected particle corresponds more or less to the sieve diameter. The geodesic length and the fiber diameter are suited very well for the characterization of fibers.

There are numerous and very application-specific shape parameters. The aim is to get extra morphological parameters in addition to particle size, whereby the particle characteristics can be better or basically described. Examples are “aspect ratio AD”, the ratio of length to width of the particles, “circularity ZK”, an indicator for particle deviation from the ideal circle and “concavity index C”, which reflects the ratio of area difference of convex envelope and area of the particle to convex envelope. Another important shape parameter is “perimeter”, which displays the particle coverage.

/1/ ISO 13322-2: Particle size analysis – Image analysis methods – Part 2: Dynamic image analysis methods

/2/ ISO 9276-6 Representation of results of particle size analysis – Part 6: Descriptive and quantitative representation of particle shape and morphology

A detailed description of particle shape can be found HERE.

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